Isolated chordal shortening: a novel mechanism of functional mitral regurgitation
نویسندگان
چکیده
منابع مشابه
Percutaneous septal sinus shortening: a novel procedure for the treatment of functional mitral regurgitation.
BACKGROUND The septal-to-lateral (SL) mitral annular diameter is increased in functional mitral regurgitation (MR). We describe a novel percutaneous technique (the percutaneous septal sinus shortening system) that ameliorates functional MR in an ovine model. METHODS AND RESULTS Sheep underwent rapid right ventricular pacing to obtain moderate to severe functional MR with SL enlargement. The p...
متن کاملChordal force distribution determines systolic mitral leaflet configuration and severity of functional mitral regurgitation.
OBJECTIVES The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these have to comply with the chordal force distribution defined by the chordal coap...
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BACKGROUND Mitral regurgitation (MR) conveys adverse prognosis in ischemic heart disease. Because such MR is related to increased leaflet tethering by displaced attachments to the papillary muscles (PMs), it is incompletely treated by annular reduction. We therefore addressed the hypothesis that such MR can be reduced by cutting a limited number of critically positioned chordae to the leaflet b...
متن کاملActive adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.
BACKGROUND In patients with left ventricular infarction or dilatation, leaflet tethering by displaced papillary muscles frequently induces mitral regurgitation, which doubles mortality. Little is known about the biological potential of the mitral valve (MV) to compensate for ventricular remodeling. We tested the hypothesis that MV leaflet surface area increases over time with mechanical stretch...
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Percutaneous transvenous mitral annuloplasty (PTMA) has evolved as a latest procedure for the treatment of functional mitral regurgitation. It reduces mitral valve annulus (MVA) size and increases valve leaflet coaptation via compression of coronary sinus (CS). Anatomical considerations for this procedure were elucidated in the present study. In 40 formalin fixed adult cadaveric human hearts, r...
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ژورنال
عنوان ژورنال: Archives of Medical Science - Aging
سال: 2020
ISSN: 2657-7941
DOI: 10.5114/amsa.2020.94952